| DATE | OPPONENT | LOCATION | TIME/RESULT | TV |
| Sun, Oct. 23 | Chadron State (Exh.) | Lincoln, Neb. | W, 87-60 | |
| Sun, Oct. 30 | Colorado | Boulder, Colo. | L, 72-61 | |
| Mon, Nov. 7 | Maine | Lincoln, Neb. | W, 79-66 | BTN+ |
| Thu, Nov. 10 | Omaha | Lincoln, Neb. | W, 75-61 | BTN+ |
| Thu, Nov. 17 | St. John's | Queens, N.Y. | L, 70-50 | |
| Sun, Nov. 20 | Arkansas-Pine Bluff | Lincoln, Neb. | W, 82-58 | BTN |
| Thu, Nov. 24 | Oklahoma | Orlando, Fla. | L, 69-56 | ESPN |
| Fri, Nov. 25 | Memphis | Orlando, Fla. | L, 73-61 | |
| Sun, Nov. 27 | Florida State | Orlando, Fla. | W, 75-58 | ESPNews |
| Wed, Nov. 30 | Boston College | Lincoln, Neb. | W, 88-67 | ESPNU |
| Sun, Dec. 4 | Creighton | Omaha, Neb. | W, 63-53 | FS1 |
| Wed, Dec. 7 | Indiana | Bloomington, Ind. | L, 81-65 | BTN |
| Sat, Dec. 10 | Purdue | Lincoln, Neb. | L, 65-62 | BTN |
| Sat, Dec. 17 | Kansas State | Kansas City, Mo. | L, 71-56 | Big 12 Now |
| Tue, Dec. 20 | Queens U. of Charlotte | Lincoln, Neb. | W, 75-65 | BTN+ |
| Thu, Dec. 29 | Iowa | Lincoln, Neb. | W, 66-50 | BTN |
| Tue, Jan. 3 | Michigan State | East Lansing, Mich. | L, 74-56 | BTN |
| Sat, Jan. 7 | Minnesota | Minneapolis, Minn. | W, 81-79 | BTN |
| Tue, Jan. 10 | Illinois | Lincoln, Neb. | L, 76-50 | BTN |
| Fri, Jan. 13 | Purdue | West Lafayette, Ind. | L, 73-55 | BTN |
| Wed, Jan. 18 | Ohio State | Lincoln, Neb. | W, 63-60 | BTN |
| Sat, Jan. 21 | Penn State | University Park, Pa. | L, 76-65 | BTN |
| Tue, Jan. 24 | Northwestern | Lincoln, Neb. | L, 78-63 | BTN |
| Sat, Jan. 28 | Maryland | College Park, Md. | L, 82-63 | BTN |
| Tue, Jan. 31 | Illinois | Champaign-Urbana, Ill. | L, 72-56 | BTN |
| Sun, Feb. 5 | Penn State | Lincoln, Neb. | W, 72-63 | BTN |
| Wed, Feb. 8 | Michigan | Ann Arbor, Mich. | L, 93-72 | BTN |
| Sat, Feb. 11 | Wisconsin | Lincoln, Neb. | W, 73-63 | BTN |
| Tue, Feb. 14 | Rutgers | Piscataway, N.J. | W, 82-72 | BTN |
| Sun, Feb. 19 | Maryland | Lincoln, Neb. | W, 70-66 | FS1 |
| Sat, Feb. 25 | Minnesota | Lincoln, Neb. | W, 78-67 | BTN |
| Tue, Feb. 28 | Michigan State | Lincoln, Neb. | L, 80-67 | BTN |
| Sun, March 5 | Iowa | Iowa City, Iowa | W, 81-77 | BTN |
